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DNA

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Extending the genomic record of human diversity

The genetic material of any two humans is 99.9% identical, but the small differences that do exist between our genomes provide a record of the complex evolutionary history we have undergone as a species. Over the past decade, scientists have sequenced a large number of... click to read more

  • Anders Bergström | Postdoctoral Research Fellow at Wellcome Sanger Institute, Cambridge, UK; The Francis Crick Institute, London, UK
Views 311
Reading time 4 min
published on Mar 25, 2021
The inanimate building-blocks for a living synthetic cell

In the field of "bottom-up" synthetic biology, we aim to build lifelike systems from inanimate building blocks. From this approach, we hope to gain deeper insights into the fundamental processes of life and develop new technological innovations. One such significant and possibly the most remarkable... click to read more

  • Kai Libicher | PhD student at Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany
  • Hannes Mutschler | Professor at Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany
Views 1582
Reading time 3.5 min
published on Dec 22, 2020
Vicious Circles – how changes in the shape of DNA can drive cancer

The diploid human genome contains 23 pairs of chromosomes whose DNA encodes genes for life activities, such as cell division. Cancer corrupts those genes, making growth-promoting genes more active (oncogenes) or growth-inhibiting genes (tumor suppressors) less active. One of the most common genetic alterations causing... click to read more

  • Sihan Wu | Postdoctoral Research Fellow at Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA, USA
  • Paul S. Mischel | Professor at Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA, USA
Views 1568
Reading time 3.5 min
published on Aug 17, 2020
Capturing the past using DNA from Sacred Ibis Mummies

Animals were significant to the ancient Egyptians as they considered them Gods living on earth. By far, the most numerous mummies found are those of the Sacred Ibis, worshipped as the incarnation of the God Thoth. Thoth was the God responsible for maintaining the universe,... click to read more

  • Sally Wasef | Lecturer at Australian Research Centre for Human Evolution, Environmental Futures Research Institute, Griffith University, Queensland, Australia
  • David Lambert | Professor at Australian Research Centre for Human Evolution, Environmental Futures Research Institute, Griffith University, Queensland, Australia
Views 1852
Reading time 3.5 min
published on Jul 6, 2020
The genetic metabolic component of anorexia nervosa

Anorexia nervosa is the deadliest psychiatric disorder and is notoriously challenging to treat. Currently, no medications are effective in its treatment, in part because we do not have a clear understanding of its biological basis. Despite myriad misconceptions, anorexia nervosa does not discriminate and can... click to read more

  • Zeynep Yilmaz | Assistant Professor at Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
  • Cynthia M. Bulik | Distinguished Professor at Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Karolinska Institutet, Stockholm, Sweden
Views 3319
Reading time 3.5 min
published on Feb 27, 2020