cancer
number of breaks: 22
Tobacco smoking and other exposures shut off cancer-fighting genes
Cancer is a genetic disease caused by mutations in DNA. Most mutations are substitutions of single nucleotides, the basic building blocks of DNA. Mutations occur over time due to natural processes like faulty DNA repair or from external sources like ultraviolet light. Researchers have discovered... click to read more
Low and Mighty: How Low-Affinity Antibodies Boost Cancer Immunotherapy
Our body is constantly guarded by our immune system, which defends us from external threats like viruses and bacteria, and even internal rogue cells that can become cancerous. Antibodies, which are special proteins in our bodies, play a key role in this defence. They work... click to read more
Engineered probiotic boosts cancer therapy
Cancer immunotherapy has revolutionized cancer treatment in the past decade. In principle, cancer immunotherapy works by improving a patient's immune system to recognize and eliminate cancer cells. Our immune system detects and attacks foreign cells or substances, such as bacteria or viruses. Despite coming from... click to read more
New chemistry in unusual bacteria displays drug-like activity
Where do drugs come from? Most clinical molecules are either produced by chemists in a laboratory, or naturally in living organisms. While synthetic chemistry is a pipeline to drug discovery, nature-made molecules continue to have an important role as drug templates. Certain soil bacteria called... click to read more
Floppy proteins and the hidden sequences they use to communicate
When the first protein structure was solved in 1958, scientists knew they had broken into a new frontier of biology. They felt that a protein’s structure would reveal all the secrets of its function, and almost 70 years down the line, over 150,000 structures have... click to read more
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