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Neurobiology

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Two hits in one – the neurobiology of schizophrenia

Schizophrenia is a severe psychiatric disorder, affecting about one percent of the population worldwide. Perturbation of pre-natal development is known to contribute to the disease, although onset typically occurs between late adolescence and early adulthood. This led to formulation of the ‘two-hit’ hypothesis: the disruption... click to read more

Views 213
Reading time 3 min
published on Jan 30, 2023
Does bacteria control our appetite?

Our gut microbial community is not as stable as one might think. Our diet has a big impact on the type and amount of bacteria we have in our gut. Every time we eat, we are not only satisfying our nutritional needs, but we are... click to read more

Views 232
Reading time 4 min
published on Jan 30, 2023
Mitochondria as microlenses in the eye – the evolution of an improved camera sensor

The back of the eye is lined with a layer of specialized light-sensitive neurons in the retina, arranged in a mosaic, called photoreceptors. Each photoreceptor has a tapered elongated shape—like a bottle—oriented perpendicular to the retina and pointing toward the pupil of the eye. The... click to read more

  • John M. Ball | Staff Scientist at Retinal Neurophysiology Section, National Eye Institute, National Institutes of Health
  • Wei Li | Senior Investigator at Retinal Neurophysiology Section, National Eye Institute, National Institutes of Health
Views 1241
Reading time 4 min
published on Oct 21, 2022
Heart Disease And Brain Blood Flow Regulation: Prelude To Dementia

The brain regulates changes in its own blood flow depending on how active its cells (neurons) are, by a mechanism called neurovascular coupling. When neurons become active, they send messages to nearby blood vessels causing them to dilate and bring in more blood. This increased... click to read more

  • Osman Shabir | Postdoctoral Research Fellow at University of Sheffield, Sheffield, United Kingdom
Views 1305
Reading time 3.5 min
published on Jul 25, 2022
Solving the puzzle behind COVID-19 induced smell loss

Smell is one of the fundamental senses in life: responsible for the recognition of environmental hazards, such as gas leaks, smoke inhalation, and spoiled foods, and yet also essential to our ability to enjoy meals beyond simple nourishment, appreciate the scents that define our environment,... click to read more

  • Marianna Zazhytska | Postdoctoral Research Fellow at Mortimer B. Zuckerman Mind, and Brain and Behavior Institute, Columbia University, New York, USA
  • Jonathan B. Overdevest | Assistant Professor at Mortimer B. Zuckerman Mind, and Brain and Behavior Institute, Columbia University, New York, USA
Views 895
Reading time 3.5 min
published on Jul 18, 2022