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obesity

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Genetic determinants of thinness and obesity: cards of the same deck

Obesity is a major public health concern worldwide, with high prevalence paralleling an increasingly "obesogenic" environment that promotes a sedentary lifestyle and poor-quality food choices. However, even within this environment, some people are able to maintain a healthy body mass index (BMI, defined as weight... click to read more

  • Fernando Riveros-Mckay | Postdoctoral Research Fellow at Wellcome Sanger Institute, Cambridge, United Kingdom
  • Inês Barroso | Director of Research at MRC Epidemiology Unit, University of Cambridge, Cambridge, UK
Views 347
Reading time 3.5 min
published on Jul 12, 2019
Gut bacteria orchestrate the transmission of overweight from mother to babe

Women who are overweight during pregnancy often deliver large babies by cesarean section, who have a greater chance of becoming overweight themselves as they grow older. A popular explanation for this mother-infant transmission of overweight is that the mother vaginally transfers "obesogenic" bacteria to her... click to read more

  • Anita L. Kozyrskyj | Professor at Dept Pediatrics, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, USA
Views 1039
Reading time 3 min
published on Nov 14, 2018
Obesity: The heavyweight of cancer

Obesity rivals tobacco as the leading preventable risk factor leading to cancer and is associated with reduced patient survival. While most people are aware of the connection between smoking and cancer, the connection with obesity is currently underappreciated. In fact, it is estimated that obesity... click to read more

  • Daniela Quail | Assistant Professor at Goodman Cancer Research Centre, Department of Physiology, McGill University, Montreal, Canada
  • Oakley Olson | Postdoctoral Research Fellow at Department of Genetics and Development, Columbia University, New York, United States
  • Johanna Joyce | Professor at Ludwig Institute for Cancer Research, Department of Oncology, University of Lausanne, Lausanne, Switzerland
Views 1759
Reading time 4 min
published on Apr 12, 2018
A new paradigm for metabolic health: reduced intake of dietary branched-chain amino acids

Obesity is an increasing problem worldwide. While even a modest reduction in weight can improve the health of overweight and obese people, and reduce the risk of developing associated diseases such as diabetes, cardiovascular disease, and cancer, most people have trouble losing weight by cutting... click to read more

  • Dudley W. Lamming | Assistant Professor at Division of Endocrinology, Diabetes and Metabolism, University of Wisconsin-Madison School of Medicine and Public Healt, Madison, USA
Views 3477
Reading time 3 min
published on Feb 22, 2018
The colour beige: heating up the fat

In mammals, adipose tissue is a specialized tissue that functions as the major storage site for fat. When glucose supplies are low (for example when an organism is food-deprived), the stored fat can be used to produce energy, so that the organism may be constantly... click to read more

  • Caterina Da Rè | Postdoctoral Research Fellow at Department of Molecular Biology, University of Geneva, Switzerland
Views 1918
Reading time 3.5 min
published on Apr 1, 2016