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Health & Physiology

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How much can antibiotic prescription rates be reduced through targeted interventions?

Antimicrobial resistance (AMR) is when bacteria, parasites, viruses, and fungi become resistant to the drugs used to treat infections. This can occur either naturally, or because people overuse and misuse antimicrobial medicines, such as antibiotics, which can speed up the development of resistance. AMR is... click to read more

  • Kyaw Zay Ya | PhD student at Swiss Tropical and Public Health Institute
  • Mark Lambiris | Postdoctoral Research Fellow at University of Basel
  • Günther Fink | Professor  at Swiss Tropical and Public Health Institute
Views 1196
Reading time 3 min
published on Oct 11, 2023
Visualizing the initial steps of blood clotting by SARS-Cov2 Spike protein

SARS-Cov-2 is a respiratory virus responsible for COVID-19 infections that can be severe or even fatal. Peculiar to SARS-Cov-2, compared to other coronaviruses, is its tendency to lead to blood clotting defects, which are involved in the major causes of severe COVID-19 complications (like microthrombosis,... click to read more

Views 1235
Reading time 3.5 min
published on Oct 9, 2023
Writing cell memory: how Histones play a role in Epigenetic Memory

Expression of a correct set of genes at the right time is crucial for cells to maintain their cell-type specific function. Epigenetic cell memory supports maintenance of such gene expression programs, with specific chromatin states regulating which genes to express or to keep silent. Chromatin... click to read more

  • Valentin Flury | Postdoctoral Research Fellow at University of Copenhagen
  • Anja Groth | Professor at University of Copenhagen
Views 1388
Reading time 4 min
published on Oct 4, 2023
How HIV-infected cells use immune checkpoints to evade the human immune system

About 38 million people live with Human Immunodeficiency Virus (HIV) worldwide and hopes for a significant reduction of new transmissions have only partially materialized. In contrast to other infectious diseases that can be readily cured with short-term antimicrobial treatment, HIV-1 infection remains incurable and requires... click to read more

Views 956
Reading time 4 min
published on Sep 27, 2023
Age-induced unsealing of the "Pandora's box": resurrection of endogenous retroviruses

Human evolution is like a tightrope walker with viruses – in a delicate balance. Endogenous retroviruses (ERVs), once part of ancient retroviral infections, are now permanently fixed in our genome. Most of them, including human ERVs (HERVs), like landmines buried in the past, accumulate mutations... click to read more

Views 880
Reading time 3.5 min
published on Sep 20, 2023